A new Team Member – Priyanka Dahate

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We have a great pleasure to introduce our new Team Member – Priyanka Dahate, who joined Max Planck Research Group as a PhD student within the Implementation PhD programme in collaboration with a biopharmaceutical company from Wrocław, Captor Therapeutics and Structural Biology Core Facility.

Here is what Priyanka wants us to know about herself.

I am very fascinated by the basic sciences and hence pursued Masters in Biochemistry from the University of Hyderabad, India. I worked with Dr. Ravi Kumar Gutti for my dissertation, which helped me to realize, how the biological processes are timed to an extraordinary level of precision while regulated at diverse levels to maintain the cellular homeostasis.

With a keen interest in exploring the different facets of biological processes, I set off to work as a Project Junior Research fellow with Dr. Rajan Sankaranarayanan’s laboratory in one of the leading research institute, CSIR-CCMB, Hyderabad in India. We elucidated the physiological role of an enzyme called Animalia-specific tRNA deacylase which tackles the errors made by the mis-selection of tRNA during the translation ultimately regulating the proteostasis using a combination of structural, biochemical and cell biology tools. During my venture, I could also appreciate structure biology along with the cell biology experiments done in collaboration with Dr. P. Chandrashekar. I was very perplexed by the Protein Quality Control pathways governing the cellular homeostasis, particularly the Ubiquitin Proteasome System and its implications in human health and pathologies because of its versatility and complexity, which also makes it an attractive target for pharmacological purposes.

The project here at MCB in collaboration with Captor Therapeutics, Wrocław offers an excellent platform to investigate the intricacies of Ubiquitin Proteasome System through the lens of structural biology, by using state-of-the-art method cryo-electron microscopy (cryo-EM) and I am very enthralled to work with the best of people in this journey!

We are happy to have Priyanka on board!