Welcome to the Max Planck Research Group website!
Research in the Glatt lab combines structural biology (x-ray crystallography and electron microscopy), molecular biology, protein biochemistry, biophysics, and cell biology to understand specific regulatory mechanisms of protein synthesis.
We use X-ray crystallography to study how proteins interact with other molecules (i.e. tRNA) and gain detailed knowledge about macromolecular assemblies and their role in post-transcriptional regulation.
We work mainly on HEK293 cells that are our source of human tRNAs and human proteins involved in tRNA modification process. Our main techniques are transfection and lentiviral transduction to modulate levels of proteins of interest.
Last November scientists from Glatt lab compiled together the latest advances on Elongator protein 3 (Elp3) and its acetyl-transferase activity. The aim of Abbassi et al.’s review was to explain more clearly the... READ MORE
To grow efficiently, yeast often need to swich from glucose to galactose and backwords. This is why they developed a simple, yet very efficient mechanism composed of three proteins that turns on when... READ MORE
A few months back our Master student, Konrad has been granted with the Erasmus+ STUDY mobility scholarship and got the opportunity to spend a semester in Heidelberg, Germany working on a research project... READ MORE